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KMID : 0381319770160010001
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Korean Journal of Occupational Health
1977 Volume.16 No. 1 p.1 ~ p.11
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The Effects of Age, Body Size and Ventilatory Functions on Pulmonary Diffusing Capacity
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조규상/Cho, Kyu Sang
정치경/이승한/Chung, Chee Kyung/Lee, Seung Han
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Abstract
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We measured the pulmonary diffusing capacity for carbon monoxice (D_(LCO)) by single breath method in groups of 47 healthy workers and 95 pneumoconiosis patients from coal mines, in order to study the normal limits of (D_(LCO)) for the healthy Korean workers and the effects of age, body size and ventilatory functions on pulmonary diffusing capacity.
The results obtained were as follows;
1. In healthy workers, pulmonary diffusing capacity was significantly correlated with age, height and body surface area and the average (D_(LCO)) was 32.2±7.5㎖/min/㎜Hg.
2. In healthy workers, the prediction equation for (D_(LCO)) versus age and body surface area was (D_(LCO))(㎖/min/㎜Hg)＝{27.88－0.243×age(yrs)}×BSA(㎡) with the standard error of estimate of 3.5㎖/min/㎜Hg.
3. There was a definite correlation between (D_(LCO)) and lung volume (V_(A)) during the breathholding and the prediction equation for the healthy workers was (D_(LCO))(㎖/min/㎜Hg)＝3.13＋6.33×(V_(A))(liter) with the standard error of estimate of 6.1㎖/min/㎜Hg
4. In healthy workers, (D_(LCO))/(V_(A)) ratio was significantly correlated with the age and the prediction equation relating (D_(LCO))/(V_(A)) and age was (D_(LCO))/(V_(A))(㎖/min/㎜Hg/liter)＝9.05－0.056×age(yrs) with the standard error of estimate of 1.21 ㎖/min/㎜Hg/liter.
5. In healthy workers and pneumoconiosis patients, (D_(LCO)) showed a positive correlation with vital capacity, vital capacity/predicted vital capacity×100, peak flow rate, maximal expiratory flow rate, and maximal mid-expiratory flow and a negative correlation with residual volume/total lung capacity×100.
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